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Updated: Sep 10, 2025

Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries
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CD4/CD8-p56诱导的T细胞受体信号及其对免疫疗法的影响

Andres Oroya1,2,3, Christopher E Rudd1,2,3,4,5,6

  • 1Département de Médicine, Université de Montréal, Montréal, QC H3C 3J7, Canada.

Biomolecules
|August 28, 2025
PubMed
概括

T细胞的激活依赖于通过CD4/CD8共受体的p56<0xE2><0xBB>ck激酶信号. 这一过程对于仿真抗原受体 (CAR) T细胞疗法至关重要,并且由PD-1等免疫检查点调节.

关键词:
卡尔T细胞T细胞受体癌症免疫疗法其他国家蛋白质化信号传输

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