相关实验视频

Updated: Sep 10, 2025

Author Spotlight: Advancing Antibiotic Resistance Research Using an Efflux-Deficient Bacterial Strain and a Single-Copy Gene Expression System
05:06

Author Spotlight: Advancing Antibiotic Resistance Research Using an Efflux-Deficient Bacterial Strain and a Single-Copy Gene Expression System

Published on: January 5, 2024

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寻找缺失的IMP基因:在拉丁美洲流通的抗卡巴胺细菌的自动化分子测试中克服Imipenemase的IMP基因脱落

Jose Arturo Molina-Mora1, Ángel Rojas-Varela1, Christopher Martínez-Arana1

  • 1Centro de Investigación en Enfermedades Tropicales & Facultad de Microbiología, Universidad de Costa Rica, San José 11501-2060, Costa Rica.

Antibiotics (Basel, Switzerland)
|August 28, 2025
PubMed
概括

一个新的定制的qPCR测试提高了碳酶基因的检测,克服了自动化测试中的假阴性. 这一进展对于全球对抗卡巴耐药性感染的管理至关重要.

关键词:
哥斯达黎加一个IMP拉丁美洲抗微生物耐药性碳烯基因脱落情况实验室结果不一致量身定制的 qPCR全基因组测序

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Development of Antibiotic Resistance01:30

Development of Antibiotic Resistance

Antibiotic resistance is a major public health concern that arises when bacteria evolve mechanisms to withstand the effects of antibiotic treatments. This resistance can be intrinsic, acquired through genetic mutations, or transferred between bacteria via horizontal gene transfer. The development of antibiotic resistance poses significant challenges in treating bacterial infections and necessitates ongoing research to develop new therapeutic strategies.Intrinsic resistance occurs when bacterial...
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