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干眼和梅博姆腺功能障碍对眼的功能和情绪影响

Liat Gantz¹, Avi Besser², Rivki Bloom¹

¹Department of Optometry and Vision Science, Jerusalem Multidisciplinary College, Jerusalem 91010, Israel.

|August 28, 2025

概括

眼睛干燥和梅博米腺功能障碍显著影响了角质球患者的生活质量. 干眼症状对情绪和功能健康的影响比梅博姆腺功能障碍更大.

科学领域:

眼科眼科
角膜疾病
干眼疾病

背景情况:

干眼 (DE) 和角 (KC) 对患者的健康有负面影响.
在KC患者中,ED症状和征兆的发生率较高.
在DE中持续摩擦眼睛可能有助于KC的发展.

研究的目的:

评估干眼 (DE) 和梅博米腺功能障碍 (MGD) 对眼 (KC) 患者的生活质量的影响.
将一般DE与MGD对功能 (KEPAQ-F) 和情感 (KEPAQ-E) 生活质量的影响进行比较.
确定DE/MGD的临床症状与患者报告的结果之间的关系.

主要方法:

在KC患者 (18至70岁) 填写了OSDI,MGDQ和KEPAQ问卷.
临床评估包括撕裂时间 (NITBUT),希尔默测试和美图.
用皮尔森相关性和路径分析来评估DE/ MGD和KEPAQ分数之间的关系.

主要成果:

49%的KC参与者患有DE,33%患有MGD.
这两种症状与KEPAQ-E和KEPAQ-F得分有负相关性.
这种症状对生活质量的影响比MGD更大.

结论:

在KC患者中,DE和MGD显著降低了情绪和功能生活质量.
在患者报告的结果上,ED症状具有更明显的负面影响.
评估和管理DE对于改善KC患者的整体福祉至关重要.

关键词:

KEPAQ (角质终点评估问卷)眼睛干燥情感上的影响功能影响角质球梅腺功能障碍 (MGD)生活质量

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