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开发一种计算效率高的CFD方法,用于血液流量分析,并将其应用于治疗规划

Soichiro Fujimura^1,2, Haruki Kanebayashi^2,3, Kostadin Karagiozov⁴

¹Department of Mechanical Engineering, Tokyo University of Science, Tokyo 125-8585, Japan.

Bioengineering (Basel, Switzerland)

|August 28, 2025

概括

一种新的计算流体动力学 (CFD) 方法使用多孔介质模型进行高效的流转器支架 (FDS) 分析. 这种方法大大降低了脑内动脉瘤治疗计划的计算成本.

科学领域:

生物医学工程
医学成像
计算科学

背景情况:

内动脉瘤带来严重的破裂风险,导致高死亡率.
流量转移支架 (FDS) 是复杂动脉瘤的关键内血管治疗方法.
血液动力学分析对于FDS治疗结果至关重要,但传统方法在计算上昂贵.

研究的目的:

开发一个计算效率高的计算流体动力学 (CFD) 方法来分析流转器支架 (FDS) 的部署.
为了使内动脉瘤的临床治疗计划能够进行实用和快速的血液动力学分析.

主要方法:

一个新的多孔介质模型被集成到CFD中,考虑到局部FDS电线密度的变化.
根据虚拟支架模拟,FDS区域被建模为一个空心圆柱体,其阻力在空间上有所变化.
该方法与使用常规电线解决CFD的15个临床病例进行了验证.

主要成果:

新的CFD方法实现了超过90%的计算资源 (网格元素,数据大小,分析时间) 的减少.
关键的血液动力学参数与传统方法有很强的一致性 (误差<5%,R2>0.98).
该方法促进了不同FDS策略和结果的比较 (例如,总填充与封闭).

结论:

拟议的多孔介质CFD方法为FDS分析提供了计算效率高和准确的替代方案.
这项进展支持基于血液动力学的, 实际治疗内动脉瘤.
能够对FDS大小,位置和辅助治疗进行可靠的评估.

关键词:

计算流体动力学流量转向支架血液动力学大脑内动脉瘤多孔介质模型

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