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微生物群与心脏健康之间的联系的系统视角:文献综述

Ionica Grigore¹, Oana Roxana Ciobotaru², Delia Hînganu³

¹Department of Morphological and Functional Sciences, Faculty of Medicine and Pharmacy, "Dunarea de Jos" University of Galați, 35, Al. I. Cuza Street, 800216 Galați, Romania.

Life (Basel, Switzerland)

|August 28, 2025

概括

心血管健康与脂质水平,代谢物,肠道细菌和口腔健康有关. 解决这些相互关联的因素对于改善住院心脏病患者的治疗结果至关重要.

科学领域:

综合性心血管病理学
心血管疾病的系统因素的相互作用.

背景情况:

心血管疾病是全球死亡的主要原因.
长期住院治疗心血管疾病的人数正在增加.
系统因素如脂质代谢,代谢物,肠道微生物群和口腔健康影响心血管结果.

研究的目的:

在心血管病理学中审查脂质代谢,循环代谢物,肠道微生物群和口腔健康的相互联系.
突出这些因素在炎症和心脏代谢风险中的作用,特别是在住院患者中.

主要方法:

对2015年至2024年间发表的研究进行叙述性审查.
在PubMed,Scopus和Web of Science进行的搜索.
关键词包括"脂质概况"",新陈代谢"",肠道微生物群"",口腔健康"和"心血管疾病".
包括原始研究,元分析和专注于住院心脏病患者的评论.

主要成果:

改变的脂质特征,肠道失调 (例如TMAO水平),代谢失衡和口腔炎之间存在显著的相互关系.
这些因素导致全身炎症,使心血管预后恶化.
尽管研究是孤立的,但整合所有四个领域的研究却很少.

结论:

综合性心血管护理应包括监测脂质代谢,代谢体变化,肠道微生物平衡和口腔状态.
肠道微生物群扮演着双重的角色;平衡的微生物群支持平衡,而失调促进炎症和不良心脏结果.
开发综合性查工具和个性化干预措施对于改善心脏病弱势群体的结果至关重要.

关键词:

心血管疾病长期住院治疗肠道微生物群综合诊断脂质概况代谢学口腔健康问题系统性炎症

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