功能神经障碍亚型之间的并发症:全面的叙述综合
Ioannis Mavroudis1,2,3,4, Katerina Franekova2, Foivos Petridis3
1Department of Neuroscience, Leeds Teaching Hospital, NHS Trust, Leeds LS17 7HY, UK.
Life (Basel, Switzerland)
|August 28, 2025
概括
功能神经障碍 (FND) 涉及各种症状. 伴随性精神病和医疗状况很常见,影响了FND的表现和治疗,包括FCD,口和PNES等亚型.
科学领域:
- 神经学
- 精神病学
- 临床心理学
背景情况:
- 功能神经障碍 (FND) 呈现出各种症状 (运动,认知,类似发作) 不能由结构性神经疾病解释.
- 伴随性精神疾病和体质疾病对FND的临床过程,诊断复杂性和治疗结果产生重大影响.
研究的目的:
- 系统地调查主要FND亚型的精神和医学并发症:功能性认知障碍 (FCD),功能性运动障碍 (FMD) 和精神性非发作 (PNES).
- 在FND并发症中确定亚型特异性模式和共同的脆弱性.
主要方法:
- 使用系统原则和PRISMA指南进行了叙事文献审查.
- 包括在FCD,口病,PNES,PPPD和一般FND群体中的共同疾病的基础和当代研究.
- 根据FND亚型和并发症类型 (精神病或医学/体质) 组织提取的数据.
主要成果:
- 在所有FND亚型中观察到高患病率 (抑郁症,焦虑症,PTSD,分离).
- 与内化症状相关的FCD;与创伤和情绪失调相关的口病;PNES显示了最高的精神负担.
- 普遍存在的体征性并发症 (纤维肌痛,慢性疼痛,肠胃综合征,疲劳) 表明生物心理机制重叠.
结论:
- 伴随性精神病和医疗状况对于理解和管理FND至关重要.
- 特定亚型的模式需要个性化诊断和治疗策略.
- 分享生物心理社会机制支持FND频谱的综合护理模式.
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