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Updated: Sep 10, 2025

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在风险人群中的胰腺癌途径特异性基因组变化

Cecilia Monge1, Brigette Waldrup2, Francisco G Carranza2

  • 1Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.

International journal of molecular sciences
|August 28, 2025
PubMed
概括

西班牙裔/拉丁裔胰腺癌患者在TGF-Beta等关键途径中表现出明显的基因突变,SMAD2和ERBB4等特定基因更为频繁. 这些发现凸显了对特定种族的精确瘤学的需求.

关键词:
通过PI3K路径RTK/RAS路径TGF-Beta 路径TP53路径通过WNT路径癌症差异基因突变胰腺癌精准医学针对性的治疗

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