高强度划船训练后尿中代谢物变化和运动诱导肌肉损伤的潜在生物标志物查
Jie Wu1, Junjie Ding2,3, Ziyue Zhao2,3
1Department of Physical Education, Beijing Institute of Technology, Zhuhai 519000, China.
International journal of molecular sciences
|August 28, 2025
概括
这项研究表明,尿液分析可以预测运动引起的肌肉损伤 (EIMD). 研究人员确定了与EIMD相关的尿中特定代谢物变化,提供了一种非侵入性预测方法.
科学领域:
- 运动医学
- 生物化学
- 代谢学
背景情况:
- 运动引起的肌肉损伤 (EIMD) 是体力活动中常见的风险.
- 目前的EIMD预测方法缺乏非侵入性和即时性.
- 尿分析为EIMD预测提供了一个潜在的途径,但代谢物变化仍然没有特征.
研究的目的:
- 在高强度运动引起的肌肉损伤后调查尿中代谢物变化.
- 确定潜在的尿路生物标志物用于非侵入性EIMD预测.
- 探索EIMD与代谢变化之间的关系.
主要方法:
- 招募了18名没有定期运动习惯的年轻学生.
- 通过高强度划船运动引起的EIMD.
- 使用准位代谢学分析尿液代谢物,通过血液检测和疼痛评估确认EIMD.
主要成果:
- 高强度的划船运动成功诱导了EIMD.
- 尿中代谢物的显著变化被观察到,其中23个是上调的,26个是下调的.
- 已识别的差异性代谢物与能量,抗氧化代谢和运动表现有关.
结论:
- 尿中代谢物分析可以检测EIMD.
- 对EIMD预测的潜在尿路生物标志物具有高灵敏度和特异性.
- 这项研究为监测肌肉损伤提供了一种新的非侵入性方法.
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