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胆固醇结合的多离子复合纳米颗粒用于联合输送疏水性帕克利塔塞尔和疏水性miR-34a用于结肠癌治疗

Arjaree Jobdeedamrong1,2, Hye Jin Yoo1,2, Hosun Jung1,2

  • 1BK21 FOUR Program in Biomedical Science and Engineering, Department of Biomedical Science, Inha University College of Medicine, Incheon 22332, Republic of Korea.

International journal of molecular sciences
|August 28, 2025
PubMed
概括

研究人员开发了用于联合癌症治疗的新型纳米颗粒,有效地将帕克利塔塞尔和miR-34a输送到结肠癌细胞中. 这种创新的联合输送系统有望提高治疗效率并减少癌细胞的生长.

关键词:
化聚合物系统大肠直肠癌模型双药物输送基因转染效率基因化学组合共同交付的 miR-34a帕克利塔塞尔封装剂聚乙烯胺纳米复合物

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