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Updated: Sep 10, 2025

Testing Cancer Immunotherapeutics in a Humanized Mouse Model Bearing Human Tumors
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通过KIR- HLA相互作用影响免疫调节对结肠直肠癌的疗效

María Gómez-Aguilera1, Bárbara Manzanares-Martín2,3, Arancha Cebrián-Aranda4

  • 1Medical Oncology Department, Reina Sofia University Hospital, University of Cordoba, 14071 Cordoba, Spain.

International journal of molecular sciences
|August 28, 2025
PubMed
概括

杀手细胞免疫球蛋白类受体 (KIR) 和HLA相互作用显著影响转移性结直肠癌 (CRC) 的 cetuximab 疗效. 特定的KIR-HLA概况预测了更好的患者结果,指导了个性化治疗CRC的策略.

关键词:
HLA 连接体其他对抗EGFR的药物其他药物转移性结直肠癌自然杀手细胞

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