治疗慢性性疼痛的多学科阶段性方案的结果
Paul Geertsema1, Ron T Gansevoort1, Benjamin H J Doornweerd2
1Department of Nephrology, Expertise Center for Polycystic Diseases, University Medical Center Groningen, University of Groningen, P.O. Box 30.001, 9700 RB Groningen, The Netherlands.
Journal of clinical medicine
|August 28, 2025
概括
在没有自身主导性多囊性病 (ADPKD) 的患者中,多学科疼痛管理方案有效降低了慢性痛. 这种治疗也减少了对止痛药的依赖,改善了耐火性痛患者的生活质量.
科学领域:
- 肝脏病学
- 治疗疼痛
- 泌尿外科
背景情况:
- 慢性脏相关疼痛显著影响患者的生活质量.
- 自体主导性多囊性病 (ADPKD) 是疼痛的常见原因.
- 非ADPKD疼痛通常在管理方面存在挑战.
研究的目的:
- 在没有ADPKD的患者中评估与有关的多学科治疗方案.
- 评估该方案在持续缓解疼痛方面的有效性.
- 确定对止痛药的使用和生活质量的影响.
主要方法:
- 预期非ADPKD患者的病例系列,严重的性痛 (VAS ≥50).
- 逐步治疗包括非药物方法,止痛药,囊吸收/化,神经阻塞和切除术.
- 通过视觉模拟尺度 (VAS),每日止痛药剂量和生活质量得分来衡量疼痛结果.
主要成果:
- 包括12名患者,平均疼痛持续时间为1. 9年.
- 从70降至35 (短期) 和40 (长期) 的VAS得分显著下降 (p<0. 01).
- 在短期和长期随访中减少了阿片类和非阿片类止痛药的使用 (p<0.05).
结论:
- 这种多学科方案可有效缓解慢性,耐火性非ADPKD痛.
- 该方案成功地减少了这一组患者对止痛药的需求.
- 在ADPKD之外,这种方法为衰弱的相关疼痛提供了可行的治疗选择.
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