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在良性甲状腺结节的射频切除后,预测不理想反应的因素

Giacomo Di Filippo¹, Fabio Medas², Giulia Gobbo³

¹Endocrine Surgery Unit, Department of Surgery and Oncology, University of Verona, 37134 Verona, Italy.

Journal of clinical medicine

|August 28, 2025

概括

射频切除 (RFA) 有效减少良性甲状腺结节,但较大的结节,较高的ACR-TIRADS得分和增加的BMI预测不理想的结果. 需要进一步的研究来完善对RFA的患者选择.

科学领域:

内分泌学
最少侵入性手术
甲状腺学

背景情况:

射频切除 (RFA) 是一种对症状良性甲状腺结节的微创治疗方法.
预测RFA疗效和识别需要多次治疗的患者仍然是一个挑战.

研究的目的:

为了确定良性甲状腺结节RFA后低于最佳体积减小 (SVR) 的预测因素.
确定与RFA后持续症状相关的因素.

主要方法:

对50名接受一次良性甲状腺结节RFA手术的患者进行了回顾性分析.
收集临床数据,结节体积,以及手术前和后的症状 (1, 6, 12个月).
回归分析以确定SVR和症状持续性的预测因素.

主要成果:

基线结节体积,较高的ACR- TIRADS得分,以及独立预测的较高的SVR (p < 0. 05).
在12个月后,18. 4%的患者出现了持续的压缩症状.
没有发现症状持续性的显著预测因素.

结论:

在良性甲状腺结节体积减小方面,RFA有效,但有些患者会出现持续的症状.
结节体积,超声波特征 (ACR-TIRADS) 和BMI影响RFA结果,可能需要重复手术.
需要进一步的研究来确定治疗反应预测因子,以优化患者选择和RFA疗效.

关键词:

体重指数其他国家甲状腺结节减量速度

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