心脏衰竭患者的医学治疗:意大利心脏病学家的德尔菲共识
Valentina Tardivo1, Emanuele Venturini2, Gaetano M Ruocco3
1School of Geriatry, University of Medicine Turin, 10126 Turin, Italy.
Journal of clinical medicine
|August 28, 2025
概括
心脏病学家倾向于使用指导方针推的药物进行综合性心力衰竭治疗,优先考虑安全性和早期启动sacubitril/ valsartan. 他们强调个性化的护理,而不是最大的耐受剂量,以获得最佳的患者结果.
科学领域:
- 心脏病学
- 药理学
- 临床实践
背景情况:
- 遵守临床指导方针对于心力衰竭 (HF) 的最佳治疗至关重要.
- 根据目前的指导方针,研究了心脏病学家对HF临床情景的方法.
- 通过电子问卷进行的Delphi分析评估了HF会议期间的专家意见.
研究的目的:
- 调查心脏病学家对心力衰竭管理指南的实际应用.
- 确定高频专家之间治疗偏好的共识和差异.
- 了解药物使用的方法,包括利尿剂,SGLT2抑制剂和MRA.
主要方法:
- 在专注于HF的会议上向心脏病专家分发电子问卷.
- 从108名参与者 (57名男性,51名女性) 收集的数据.
- 对治疗方案和药物类别偏好的反应分析.
主要成果:
- 关于β- 阻断剂对HF预后和死亡率降低的强烈共识.
- 喜欢静脉循环利尿剂与 thiazides 结合使用;不喜欢甲.
- SGLT2 抑制剂 (SGLT2i) 降低了住院病例;对于替代MRA缺乏共识.
- 由于高血症/ 功能障碍而停止MRA,优先考虑安全性.
- 几乎一致同意在医院住院后开始使用sacubitril/valsartan.
结论:
- 97% 的心脏病学家更喜欢使用指导方针推的所有HF药物类别,根据需要调整剂量.
- 针对多种HF机制的综合治疗是优先考虑的.
- 个性化治疗策略至关重要,
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