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Updated: Sep 10, 2025

Quantification of Orofacial Phenotypes in Xenopus
09:26

Quantification of Orofacial Phenotypes in Xenopus

Published on: November 6, 2014

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基因与环境的相互作用 涉及菲律宾妇女面部裂风险

Zeynep Erdogan-Yildirim1, Jenna C Carlson2,3, Nandita Mukhopadhyay1

  • 1Center for Craniofacial and Dental Genetics, Department of Oral and Craniofacial Sciences, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA.

Genes
|August 28, 2025
PubMed
概括

这项研究探讨了菲律宾母亲口唇裂 (CL/P) 的基因与环境相互作用. 虽然没有发现显著的全基因组相互作用,但发现了母亲吸烟,维生素使用和CL/ P风险基因之间的联系.

关键词:
菲律宾带有或没有口腔裂的唇裂基因与环境的相互作用孕产妇暴露没有综合症

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Optimized Analysis of DNA Methylation and Gene Expression from Small, Anatomically-defined Areas of the Brain13:11

Optimized Analysis of DNA Methylation and Gene Expression from Small, Anatomically-defined Areas of the Brain

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Gene expression is a dynamic process that is significantly influenced by environmental factors. This interaction underlies the complex nature of biological development and the phenotypic differences observed among individuals, even among those with identical genetic makeups. Factors such as radiation, temperature, behavior, nutrition, and stress play pivotal roles in determining how genes are expressed. The concept of the reaction range is central to understanding this interaction. It posits...
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