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甲胺可降低RNASEH2突变艾卡迪-古蒂埃尔细胞的氧化损伤

Francesca Dragoni1, Jessica Garau1, Bartolo Rizzo1

  • 1IRCCS Mondino Foundation, 27100 Pavia, Italy.

Genes
|August 28, 2025
PubMed
概括

在具有RNASEH2B/ A突变的艾卡迪- 古提耶氏综合征细胞中,甲胺有效降低氧化应激并恢复线粒体功能. 这表明甲胺是治疗AGS患者炎症的潜在药物.

关键词:
艾卡迪-古蒂埃尔综合征在RNASEH2其他甲胺线粒体氧化应激

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