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Updated: Sep 9, 2025

gDNA Enrichment by a Transposase-based Technology for NGS Analysis of the Whole Sequence of BRCA1, BRCA2, and 9 Genes Involved in DNA Damage Repair
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gDNA Enrichment by a Transposase-based Technology for NGS Analysis of the Whole Sequence of BRCA1, BRCA2, and 9 Genes Involved in DNA Damage Repair

Published on: October 6, 2014

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基底体单基因BRCA1无活化:乳腺癌预后的一个生物标志物

Elza Kuznecova1, Miki Nakazawa-Miklasevica1,2, Nora Krike1

  • 1Institute of Oncology and Molecular Genetics, Riga Stradins University, Pilsonu Street 13, Block 13, LV-1002 Riga, Latvia.

Diagnostics (Basel, Switzerland)
|August 28, 2025
PubMed
概括

乳腺癌中单基体性BRCA1无活化可能表明预后有利. 这项研究确定了与这种遗传变异患者更好的结果相关的特定基因表达模式.

关键词:
BRCA1体内无活化乳腺癌不同基因表达转录组

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Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
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