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Expression of Recombinant Proteins in the Methylotrophic Yeast Pichia pastoris
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在Pichia pastoris中优化扩大复合蛋白HFBI的生产和净化

Mason A Kinkeade1, Aurora L Pagan2, Bryan W Berger2

  • 1Department of Chemical Engineering, University of Virginia, Charlottesville, VA 22903, USA.

Microorganisms
|August 28, 2025
PubMed
概括

研究人员使用Pichia pastoris优化了水蛋白HFBI (水蛋白) 的产生. 这为更广泛的工业应用提高了真菌生物表面活性剂的产量和纯度.

关键词:
卡普托MMC ImpRes公司美国联邦调查局皮奇亚牧羊人生物表面活性剂水蛋白固定金属亲和色谱多模式色谱尺寸排除色谱

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Upstream Processing01:27

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Upstream processing represents a critical phase in biomanufacturing, wherein biological systems such as microorganisms, mammalian cells, or insect cells are cultivated to produce therapeutic proteins, vaccines, enzymes, or other biologically derived products. This phase encompasses all steps from the selection and genetic manipulation of the production organism to the cultivation of cells in bioreactors under tightly controlled environmental conditions.Host Selection and Genetic OptimizationThe...
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