使用具有抗氧化和抗菌性质的肝脏水解剂制造可持续的糖
Ignė Juknienė1, Naga Pavan Kumar Reddy Jonnagiri1, Irena Mačionienė2
1Department of Food Safety and Quality, Lithuanian University of Health Sciences, Veterinary Academy, Tilzes St. 18, LT-47181 Kaunas, Lithuania.
Microorganisms
|August 28, 2025
概括
用猪肝蛋白水解剂丰富的功能性糖具有增强的抗氧化和抗菌特性. 这些创新产品以消费者友好的形式提供潜在的健康益处.
科学领域:
- 食品科学
- 生物化学
- 微生物学
背景情况:
- 糖果产品提供了功能成分的流行的配送系统.
- 蛋白质水解物具有生物活性,包括抗氧化和抗菌作用.
- 猪肝是有价值的蛋白质水解剂的潜在来源.
研究的目的:
- 开发功能性糖,其中包含猪肝蛋白水解物.
- 评估这些水解剂对抗氧化和抗菌活性的影响.
- 评估开发的糖的消费者可接受性和物理化学特性.
主要方法:
- 消费者可接受性 (OA) 测试,以优化性矩阵.
- 使用ABTS•+和DPPH•试验对抗氧化活性进行分析.
- 对主要病原体 (李斯特菌,大肠杆菌,沙门氏菌) 的抗菌作用的评估.
- 微生物安全性和的物理化学特性.
主要成果:
- 猪肝水解剂显著提高了糖的抗氧化能力.
- 样本GC5Pa24Ag (以帕帕因水解,以阿加为基础) 显示出最高的抗氧化活性 (67. 6 ± 0. 98 μmol/ g ABTS•+, 49. 14 ± 1. 00% DPPH•).
- 用素水解的样本对L.单细胞菌,大肠杆菌和S. Typhimurium具有显著的抗菌活性.
- GC5Pa24Ag表现出最广泛的抗菌谱,抑制区为29.0±0.2毫米.
结论:
- 猪肝蛋白水解剂可以有效地纳入功能性糖.
- 这些功能性糖果具有显著的抗氧化和抗菌特性.
- 开发的产品提供了一种新,消费者友好的健康效益方法.
相关概念视频
Bioavailability Enhancement: Drug Permeability Enhancement
352
After oral administration, poor permeability often limits the rate at which drugs are absorbed through the intestinal epithelium. Enhancing drug permeability is crucial for effective therapy, and several strategies have been developed to overcome this challenge.One effective strategy involves the use of lipid-based formulations. These formulations enhance dissolution and solubility, targeting physiological mechanisms to increase drug absorption. This includes stimulating bile salt secretion,...
352
Bioavailability Enhancement: Drug Stability Enhancement and GI Retention
332
Improving a drug's stability in the gastrointestinal (GI) tract is paramount for enhancing its bioavailability and therapeutic effectiveness. Various strategies are employed to protect the drug from the harsh gastric milieu and to ensure its release and absorption at the desired site within the GI tract.Polymer coatings are one such method used to shield drugs from the stomach's acidic environment. By preventing premature drug release, these coatings improve the bioavailability of unstable...
332
Formulation and Manufacturing Process: Physical Attributes of Generic Tablets and Capsules
420
Bioequivalence in generic drugs, such as tablets and capsules, refers to their pharmaceutical equivalence to the brand-name counterparts. However, for therapeutic equivalence, manufacturers must also consider physical attributes like size, shape, and weight (FDA Guidance for Industry, December 2003). Discrepancies in these aspects could impact patient compliance and cause medication errors. For instance, swallowing difficulties, often experienced with larger tablets or capsules, can lead to...
420
Oral Drug Delivery Systems: Introduction
279
Oral drug delivery is the most common route of administration due to its convenience, cost-effectiveness, and high patient compliance. It enables precise formulation to ensure proper drug dosage and bioavailability. The development of oral dosage forms considers drug properties such as solubility, stability, and absorption to optimize therapeutic efficacy.Tablets, capsules, liquids, and chewable formulations enhance drug stability, mask undesirable tastes, and improve patient experience.
279
Oral Drug Delivery Systems: Delayed-Release Systems
222
Delayed-release drug delivery systems are specialized pharmaceutical formulations designed to postpone the release of active compounds until the drug reaches a specific region of the gastrointestinal (GI) tract, typically the intestine. These systems are essential for drugs that may cause gastric irritation, are unstable in acidic environments, or need to exert therapeutic effects locally in the intestinal or colonic regions.The core feature of delayed-release systems is the use of enteric...
222
Production of Organic Acids
105
Lactic acid, an important organic acid extensively applied in food, pharmaceutical, and biodegradable polymer industries, is primarily produced via microbial fermentation. This method is favored over chemical synthesis due to its environmental sustainability and capacity for enantiomerically pure product formation. Among various microbial processes, the fermentation of starch-based substrates stands out due to the abundance and renewability of raw materials like corn and potatoes.Hydrolysis of...
105


