益生菌在与代谢功能障碍相关的脂肪肝炎的治疗潜力:综合性审查
Xueying Wang1, Zhiying Wei1, Qing Xiang1
1College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, China.
Microorganisms
|August 28, 2025
概括
代谢功能障碍相关的脂肪肝炎 (MASH) 涉及肠道微生物组的变化. 益生菌有望通过调节肠肝轴和改善症状治疗MASH.
科学领域:
- 肝病学
- 微生物学
- 胃肠病学
背景情况:
- 代谢功能障碍相关的脂肪肝炎 (MASH) 是一种进展性肝病.
- 肠道微生物失调与MASH的发病有关.
- 肠肝轴在MASH进展中起着至关重要的作用.
研究的目的:
- 审查MASH中的肠道微生物组变化.
- 在MASH中检查益生菌与肠肝轴的相互作用.
- 建立基于益生菌的MASH疗法的基础.
主要方法:
- 综合现有证据的文献审查.
- 分析与MASH相关的肠道微生物组变化.
- 评估益生菌机制,临床试验和疗效.
主要成果:
- 肠道失调是MASH发展的一个关键因素.
- 益生菌可以调节肠道微生物群,
- 有证据支持益生菌作为一种潜在的MASH治疗策略.
结论:
- 益生菌是一种有前途的MASH治疗方法.
- 需要进一步的研究来优化MASH的益生菌干预措施.
- 了解肠肝轴对于MASH治疗至关重要.
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