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Updated: Sep 9, 2025

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在传染性支气管炎病毒中,S2糖蛋白子单元确定肠道热带性

Zhenkai Dai1,2,3,4, Jing Zhang1,3,4, Ying Huang5

  • 1State Key Laboratory of Swine and Poultry Breeding Industry & Guangdong Laboratory for Lingnan Modern Agriculture, College of Animal Science, South China Agricultural University, Guangzhou 510642, China.

Microorganisms
|August 28, 2025
PubMed
概括

感染性支气管炎病毒 (IBV) 的S2子单元决定了十二指管的热带性. 这一发现确定了S2作为开发针对肠道IBV菌株的新疫苗的关键目标.

关键词:
S2子单位禽类冠状病毒十二指肠禽类疾病尖子蛋白质组织热带性病毒病原性

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Leaky Scanning02:28

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During most eukaryotic translation processes, the small 40S ribosome subunit scans an mRNA from its 5' end until it encounters the first start AUG codon. The large 60S ribosomal subunit then joins the smaller one to initiate protein synthesis. The location of the translation initiation is largely determined by the nucleotides near the start codon as there may be multiple translation initiation sites present on the mRNA.  Marilyn Kozak discovered that the sequence RCCAUGG (where R...
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