超加工食品和脆弱性:前性队列研究的证据和未来研究的影响
Elsa M Konieczynski1, Shivani Sahni2, Paul F Jacques3
1Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA 02111, USA.
Nutrients
|August 28, 2025
概括
超加工食品 (UPF) 摄入量没有增加老年人的虚弱风险. 然而,更高的UPF消费与步行速度和握力下降有关,特别是在男性中.
科学领域:
- 老年学
- 营养科学
- 流行病学
背景情况:
- 超加工食品是老年人饮食中的重要组成部分.
- 潜在的促炎途径将UPF与脆弱性联系在一起.
- 调查UPF在脆弱性发展和进展中的作用至关重要.
研究的目的:
- 检查UPF摄入量与脆弱性发展之间的关联.
- 评估UPF摄入量与脆弱成分的年度变化之间的关系.
- 通过性别和年龄来评估潜在的效果变化.
主要方法:
- 在2547名Framingham后裔群体中进行前性队列研究.
- 通过食物频率问卷和NOVA分类来评估UPF摄入量.
- 由Fried脆弱性表型定义的脆弱性;使用了后勤和线性回归模型.
主要成果:
- 在UPF摄入量和脆弱性发展之间没有发现显著的关联.
- UPF摄入量与每年体重变化无关.
- 观察到UPF摄入量与每年步行速度和握力变化之间的反向关联,特别是在男性中.
结论:
- 在中年和老年人中,增加UPF摄入量与脆弱性发展无关.
- 消耗UPF可能与肌肉强度和功能下降有关.
- 对于临床建议,需要对UPF分类进行进一步研究.
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