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相关概念视频

Types of Reversible Electrodes01:24

Types of Reversible Electrodes

7
For electrode reversibility to be maintained, all the reactants and products involved in the half-reaction must be present at the electrode. There are several types of reversible electrodes (half-cells).In metal-metal-ion electrodes, a metal balances electrochemically with a solution of its own ions. Examples are Cu2+|Cu and Zn2+|Zn. Metals that react with the solvent, like group 1 and most group 2 metals, which react with water, and zinc, which reacts with aqueous acidic solutions, cannot be...
7

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Chronic Implantation of Multiple Flexible Polymer Electrode Arrays
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基于聚胺的柔性微电极阵列用于非侵入性角膜电刺激

Víctor Manuel Carpio-Verdín1, Natiely Hernández-Sebastián1, Bernardino Barrientos-García1

  • 1Centro de Investigaciones en Óptica, A.C. Loma del Bosque 115, León 37150, Mexico.

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概括
此摘要是机器生成的。

研究人员开发了一种用于治疗视网膜退行性疾病的跨角膜电刺激 (TES) 的新型微电极阵列. 这种新电极提供了更好的空间选择性,克服了当前针对视网膜治疗的设备的局限性.

关键词:
一个MEMS灵活的电子设备微电极阵列表面微加工通过角膜进行电刺激

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科学领域:

  • 眼科 眼科
  • 生物医学工程
  • 材料科学

背景情况:

  • 通过角膜电刺激 (TES) 显示出治疗视网膜退行性疾病 (RDD) 的潜力.
  • 目前的TES电极,如DTL和ERG-JET,由于其连续的金属表面,在空间分辨率和选择性刺激方面存在限制.
  • 需要先进的TES电极,允许精确的,空间选择性的视网膜电刺激.

研究的目的:

  • 开发和验证一种具有增强空间选择性的新型跨角膜电刺激电极.
  • 为了在RDD中实现针对性激活特定视网膜区域的潜在治疗应用.
  • 评估新的微电极阵列的制造,电化学和光学性能.

主要方法:

  • 使用,和聚的表面微加工和柔性电子制造20个独立微电极阵列的制造.
  • 电气和电化学测试以评估导电性,阻抗和电荷储存能力.
  • 在可见光谱中进行电信号传输和光学传导度测试.

主要成果:

  • 制造的电极显示出Al/Ti结构的高电导率.
  • 低电化学阻抗 (791 kΩ至1.75 MΩ在11-30 Hz) 和高电荷储存容量 (1437 mC/cm2) 得到了实现.
  • 在试验室成功地证明了电信号传输和光学传导率的评估,以记录电网膜图 (ERG).

结论:

  • 开发的微电极阵列提供了空间选择性的TES,比传统电极有了显著的进步.
  • 使用Al,Ti和PI的简化,低成本的制造工艺使电极具有可重复性和可行性.
  • 这种新型电极有望改善RDD的治疗干预和先进的电网膜录像.