狗认知功能障碍综合征的诊断:一个叙述性审查
Claudia Vitturini1, Matteo Cerquetella1, Andrea Spaterna1
1School of Biosciences and Veterinary Medicine, University of Camerino, Via Circonvallazione 93/95, 62024 Matelica, Italy.
Veterinary sciences
|August 28, 2025
概括
狗的寿命延长导致狗认知功能障碍综合征 (CCDS) 的病例增加. 需要进一步的研究来确定这种类似阿尔茨海默病的可靠诊断标志物.
科学领域:
- 兽医神经学
- 比较医学
- 动物健康
背景情况:
- 狗的预期寿命增长与人类的老龄化趋势相匹配.
- 像阿尔茨海默氏症 (AD) 这样的神经退行性疾病在人类中具有相应的犬类认知功能障碍综合征 (CCDS).
- CCDS通常影响老年犬 (8岁以上),呈现出越来越大的临床挑战.
研究的目的:
- 审查目前关于CCDS死前诊断的敏感和可靠标志物的文献.
- 突出了对兽医中CCDS的标准化诊断方案的需要.
- 确定用于CCDS诊断的有前途的临床和实验室评估.
主要方法:
- 对最新的科学文献进行叙述性回顾.
- 专注于识别CCDS的敏感和可靠的生物标志物.
- 对狗的认知功能障碍现有临床和实验室评估的分析.
主要成果:
- 一些分析的参数显示出CCDS诊断的前景.
- 目前的诊断方法需要进一步验证.
- 目前还没有确定的标准诊断标记.
结论:
- 准确的死前诊断对于有效的治疗和动物福利至关重要.
- 需要进一步的研究来确认有希望的诊断标志物.
- 迫切需要标准化方案来诊断和管理CCDS.
相关概念视频
01:30Dementia
165
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
The progression of dementia is generally gradual....
165
01:26Alzheimer's Disease: Overview
666
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
666