在SARS-CoV-2大流行前,期间和后的呼吸系统病毒流行
Michele Manno1, Grazia Pavia1, Simona Gigliotti1
1Unit of Clinical Microbiology, Department of Health Sciences, "Magna Græcia" University, A.O.U. "R. Dulbecco", 88100 Catanzaro, Italy.
Viruses
|August 28, 2025
概括
COVID-19 大流行改变了呼吸系统病毒的模式,降低了流感A,但保持了鼻病毒的循环. 对于高危人群来说,接种COVID-19和流感疫苗至关重要.
科学领域:
- 病毒学
- 流行病学
- 公共卫生
背景情况:
- 随着COVID-19的流行,病毒性呼吸道感染的正常模式显著受到干扰,影响了病毒的循环和季节性.
- 了解SARS-CoV-2对其他呼吸系统病毒的影响对于管理公共卫生和临床护理至关重要.
研究的目的:
- 评估SARS-CoV-2对意大利南部病毒性呼吸道感染的频率的影响.
- 为了比较COVID-19大流行前,期间和之后的病毒循环和季节性.
- 调查SARS-CoV-2的出现如何影响其他呼吸系统病毒.
主要方法:
- 从教学医院分析鼻样本的回顾性和前性研究.
- 样本分为COVID-19前,COVID-19期间和COVID-19后的时间段.
- 鉴定了呼吸系统病毒,并分析了它们的流行率和同时感染模式.
主要成果:
- 在3930个样本中,20%的样本呈呼吸道病毒阳性;老年人 (65-98岁) 的阳性率较高.
- 在大流行前,流感A最为普遍;在大流行期间,SARS-CoV-2占主导地位. 在大流行后,SARS-CoV-2 减少,而 A 型流感增加.
- 甲型流感的流通量显著下降,而RSV的流行病学则保持稳定. 病毒共同感染的动态发生了变化.
结论:
- COVID-19 流行病显著改变了呼吸系统病毒的流行病学,在流行病后观察到持久的影响.
- 观察到A型流感的显著减少以及与SARS-CoV-2病毒的持续共流.
- 鉴于高风险群体的重叠,建议同时接种COVID-19和流感疫苗.
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