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Updated: Sep 9, 2025

A High Resolution Method to Monitor Phosphorylation-dependent Activation of IRF3
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A High Resolution Method to Monitor Phosphorylation-dependent Activation of IRF3

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在多种物种中,Poxvirus K3正义体通过向PKR-eIF2α轴调节NF-κB依赖的炎症反应

Huibin Yu1,2, Mary Eloise L Fernandez1, Chen Peng3

  • 1Department of Medical Microbiology and Immunology, School of Medicine, University of California, Davis, CA 95618, USA.

Vaccines
|August 28, 2025
PubMed
概括

哺乳动物蛋白激酶R (PKR) 基因组保持抗病毒和炎症作用,抑制转化和激活NF-κB. 毒病毒K3蛋白质对抗PKR,突出显示病毒的免疫规避策略.

关键词:
美国K3 ортолог 的使用在 NF-κB在PKR其他国家炎症反应瘤病毒化病毒

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