Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Vaccinations01:51

Vaccinations

45.3K
Overview
45.3K
Immunological Memory01:23

Immunological Memory

4.8K
Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature...
4.8K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Data from the Researcher Mental Health Observatory STAIRCASE Survey.

Journal of open psychology data·2026
Same author

The Use of Protective Equipment and Personal Monitoring in Fluoroscopy-Guided Procedures: A Case Study in Portugal.

Healthcare (Basel, Switzerland)·2026
Same author

Pharmacological Interventions in the Management of Temporomandibular Disorders: A Systematic Review and Meta-analysis.

Acta stomatologica Croatica·2026
Same author

"Can a chatbot be used in the full-text screening in a systematic review?"

International journal of medical informatics·2026
Same author

Interventions to Chemotherapy and Radiotherapy Induced Oral Mucositis: a Systematic Review and Meta-analysis.

Acta stomatologica Croatica·2026
Same author

Therapeutic drug monitoring education: The current state.

British journal of clinical pharmacology·2025

相关实验视频

Updated: Sep 9, 2025

A Method to Assess Fc-mediated Effector Functions Induced by Influenza Hemagglutinin Specific Antibodies
04:47

A Method to Assess Fc-mediated Effector Functions Induced by Influenza Hemagglutinin Specific Antibodies

Published on: February 23, 2018

7.8K

作为预测流感疫苗有效性的免疫性:系统性审查

André Miguel Martins1, Luis Félix Valero Juan2, Marlene Santos1,3

  • 1LAQV/REQUIMTE, Escola Superior de Saúde, Instituto Politécnico do Porto, Rua Dr. António Bernardino de Almeida, 4200-072 Porto, Portugal.

Vaccines
|August 28, 2025
PubMed
概括

这项研究使用血凝抑制度来模拟流感疫苗的免疫性和有效性. 较高的抗体反应与疫苗的有效性增加相关,证实了免疫性数据的重要性.

关键词:
有效性免疫性流感 的流感疫苗

更多相关视频

An Optimized Hemagglutination Inhibition HI Assay to Quantify Influenza-specific Antibody Titers
06:34

An Optimized Hemagglutination Inhibition HI Assay to Quantify Influenza-specific Antibody Titers

Published on: December 1, 2017

36.5K
Measuring Influenza Neuraminidase Inhibition Antibody Titers by Enzyme-linked Lectin Assay
08:11

Measuring Influenza Neuraminidase Inhibition Antibody Titers by Enzyme-linked Lectin Assay

Published on: September 6, 2016

19.0K

相关实验视频

Last Updated: Sep 9, 2025

A Method to Assess Fc-mediated Effector Functions Induced by Influenza Hemagglutinin Specific Antibodies
04:47

A Method to Assess Fc-mediated Effector Functions Induced by Influenza Hemagglutinin Specific Antibodies

Published on: February 23, 2018

7.8K
An Optimized Hemagglutination Inhibition HI Assay to Quantify Influenza-specific Antibody Titers
06:34

An Optimized Hemagglutination Inhibition HI Assay to Quantify Influenza-specific Antibody Titers

Published on: December 1, 2017

36.5K
Measuring Influenza Neuraminidase Inhibition Antibody Titers by Enzyme-linked Lectin Assay
08:11

Measuring Influenza Neuraminidase Inhibition Antibody Titers by Enzyme-linked Lectin Assay

Published on: September 6, 2016

19.0K

科学领域:

  • 免疫学
  • 疫苗学
  • 公共卫生

背景情况:

  • 流感疫苗接种对全球健康至关重要,需要每年对疫苗的有效性进行评估,因为疫苗的菌株在不断变化,项目投资也在不断增加.
  • 在研发过程中预测疫苗的疗效需要了解免疫性和疗效之间的联系.
  • 测量抗体反应,特别是血液凝聚抑制 (HAI) 标位,是评估疫苗免疫性的关键方法.

研究的目的:

  • 建立一个预测模型,通过HAI标量测量流感疫苗的免疫性与疫苗的疗效.
  • 分析不同菌株和群体中HAI标量与流感疫苗有效性的关系.

主要方法:

  • 从Medline和Scopus数据库中对抗流感疫苗免疫性和疗效相关的文章进行系统审查.
  • 开发和应用数学模型来评估HAI标位与疫苗有效性之间的关系.
  • 根据疫苗类型,流感病毒菌株和儿童群体的疗效进行分层分析.

主要成果:

  • 确定系数 (r2) 从0. 2579到0. 966不等,表明HAI标位与流感疫苗疗效之间存在显著的相关性.
  • 这些结果强调了抗体反应水平在确定疫苗有效性的关键作用.

结论:

  • 这项研究验证了HAI标位作为流感疫苗有效性的可靠指标.
  • 40的效率值证实了数据的稳定性和模型的预测能力.