亚洲DTP3疫苗接种趋势 (2012-2023)
Ines Aguinaga-Ontoso1,2,3, Laura Guillen-Aguinaga4,5, Sara Guillen-Aguinaga1,6
1Department of Health Sciences, Public University of Navarra, 31008 Pamplona, Spain.
Vaccines
|August 28, 2025
概括
在亚洲,疹 - 咳疫苗的第三剂量 (DTP3) 覆盖率略有增长,但面临大流行性干扰. 需要制定战略来应对疫苗接种率的下降,并确保实现免疫目标.
科学领域:
- 公共卫生
- 流行病学
- 疫苗学
背景情况:
- 第三剂 (DTP3) 覆盖率是常规免疫计划和全球疾病减少的关键指标.
- 评估DTP3覆盖率趋势对于了解免疫计划的强度和确定需要改进的领域至关重要.
研究的目的:
- 分析2012年至2023年亚洲地区和国家的DTP3疫苗接种率趋势.
- 评估COVID-19大流行对亚洲地区DTP3疫苗接种范围的影响.
主要方法:
- 利用了世卫组织/联合国儿童基金会2012-2023年全国免疫覆盖率估计 (WUENIC) 数据.
- 使用Joinpoint回归分析,按出生队列大小加权,以确定五个亚洲次区域的显著趋势变化.
- 与潜在的流行病相关的干扰相关的上下文发现.
主要成果:
- 亚洲的DTP3覆盖率每年略有增加,而2018年的趋势有所改变.
- 东南亚和南亚在2018年后出现下降,从2021年开始出现一些复苏.
- 各国数据显示出显著的异质性,在黎巴嫩和缅甸出现了显著的流行后下降,在伊拉克和菲律宾出现了复苏.
结论:
- 亚洲地区的DTP3覆盖率有明显的进步,但疫情的干扰影响了卫生系统脆弱的地区.
- 解决零剂量和退学儿童问题,加强服务连续性和打击错误信息对于实现2030年免疫目标至关重要.
- 应对亚洲不同环境的挑战和加强常规免疫计划, 需要量身定制的战略.
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