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Updated: Sep 9, 2025

A Comparative Approach to Characterize the Landscape of Host-Pathogen Protein-Protein Interactions
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A Comparative Approach to Characterize the Landscape of Host-Pathogen Protein-Protein Interactions

Published on: July 18, 2013

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针对性降解HPV上蛋白E6可降低宫癌中的瘤负担

Tracess B Smalley1, Angelo A Nicolaci2, Kim C Tran3

  • 1Department of Molecular Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 33612, USA.

Molecular therapy : the journal of the American Society of Gene Therapy
|August 28, 2025
PubMed
概括

一种新型的蛋白质溶解向基梅拉 (PROTAC) 有效地降解人类乳头瘤病毒 (HPV) E6 蛋白,抑制HPV的瘤生长. 这种向治疗也刺激免疫反应,为HPV癌症治疗提供了新的途径.

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