糖尿病与周植入炎之间的联系:来自瑞典注册研究的证据
Anna Trullenque-Eriksson1, Fernando Valentim Bitencourt2,3, Cristiano Tomasi1
1Department of Periodontology, Institute of Odontology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Journal of clinical periodontology
|August 28, 2025
概括
患有1型和2型糖尿病的人患上围植入炎的风险增加. 这项研究发现1型糖尿病的患病率更高,2型糖尿病的发病率更高.
科学领域:
- 牙科植入物学
- 内分泌学
- 公共卫生研究
背景情况:
- 牙周植入物炎是牙科植入物的一种严重并发症,影响了很大一部分患者.
- 糖尿病,包括1型 (T1D) 和2型 (T2D),是一种普遍的慢性疾病,具有全身影响.
- 了解糖尿病和周植入炎之间的相互作用对于患者的管理和治疗结果至关重要.
研究的目的:
- 调查1型糖尿病和2型糖尿病之间的联系,以及发生围植入炎的风险.
- 在糖尿病患者和非糖尿病患者中比较周植入炎的患病率和发病率.
主要方法:
- 基于2010年至2020年的瑞典全国卫生登记册的队列研究.
- 确定了四组:T1D,T2D患者和匹配的非糖尿病对照.
- 通过注册治疗来定义周植入炎;使用逻辑回归来分析患病率,并使用生存分析与倾向分数匹配来分析发病率.
主要成果:
- 与非T1D患者 (15. 2%) 相比,T1D患者的周植入炎患病率更高,患病率为1. 46.
- 在T2D (20. 5%) 和非T2D (18. 2%) 之间,患病率相似,概率为1. 06.
- 发生性周植入炎的危险比为T1D的1. 52和T2D的1. 36.
结论:
- 1型糖尿病和2型糖尿病都与周植入炎的风险增加有关.
- 在T1D患者中,周植入炎的风险增加在患病率数据中更加明显.
- 对于T2D,与周植入炎的相关性主要在发病率数据中观察到.
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