目前的3D打印技术及其在药物交付,个性化医学和制药科学方面的潜在应用
Virendra S Gomase1,2, Arjun P Ghatule3, Rupali Sharma2
1S.P. Mandali's, Prin. L. N. Welingkar Institute of Management Development & Research, Mumbai, 400019, India.
Current drug discovery technologies
|August 28, 2025
概括
3D打印技术通过实现个性化医疗和先进药物输送, 彻底改变了药学. 这项技术使得精确的剂量和量身定制的治疗方法能够改善患者的治疗结果,尽管存在挑战.
科学领域:
- 制药科学
- 生物技术
- 材料科学
背景情况:
- 3D打印正在改变药物研究, 提供精确剂量,复杂药物输送和个性化配方的解决方案.
- 它解决了制药行业的主要挑战,为更高效和针对患者的治疗铺平了道路.
- 这项技术加速了药物开发和药物输送方法.
研究的目的:
- 探索3D打印技术在药物交付,个性化医疗和制药科学中的应用.
- 通过创新的药物解决方案提高治疗结果和患者护理.
- 审查医药应用3D打印的进展.
主要方法:
- 检查了3D打印技术的进展,包括融沉积建模 (FDM),立体石刻 (SLA) 和选择性激光烧结 (SLS).
- 评估各种材料的适用性,如水凝,生物墨水和聚合物用于制药应用.
- 专注于使用这些技术生产药物输送装置,定制剂型和生物打印组织.
主要成果:
- 在制造具有精确剂量和修改释放模式的定制药物配方方面取得显著进展.
- 强调生物打印在再生医学和组织工程中的潜力.
- 展示了复杂的药物输送系统 (植入物,贴片) 的加速发展,改善了患者的坚持.
结论:
- 3D打印在个性化医疗和先进的药物输送系统中发挥着变革性的作用.
- 像FDM,SLA和SLS这样的技术对定制剂量形式和复杂设备有希望,提高治疗结果.
- 材料和技术的不断改进表明3D打印在医疗保健中的作用越来越大,
相关概念视频
01:29Issues And Trends In Healthcare Delivery System
5.8K
The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
5.8K
01:16Drug Delivery: Overview
422
The selection of a drug's delivery route depends upon its physicochemical properties, including lipid or water solubility and ionization, as well as the therapeutic requirement, such as immediate or sustained effect. These routes can be divided into three primary categories: enteral, parenteral, and topical.
Enteral delivery involves administering drugs directly through swallowing, sublingual placement, or buccal application. Orally administered drugs predominantly navigate the...
Enteral delivery involves administering drugs directly through swallowing, sublingual placement, or buccal application. Orally administered drugs predominantly navigate the...
422
01:29Microorganisms in Medicine and Therapeutics
312
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
312
01:22Drug Delivery: Miscellaneous Routes
467
Drug delivery methods like oral inhalation, nasal sprays, transdermal patches, eye drops, intravitreal injection, and rectal administration provide localized effects with reduced toxicity.
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
467