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Alessandro Ruggiero1, Giuseppe Pascarella2

  • 1Research Unit of Anesthesia and Intensive Care, Department of Medicine, Campus Bio-Medico University, Rome, Italy - alessandro.ruggiero@unicampus.it.

Minerva anestesiologica
|August 28, 2025
PubMed
概括

No abstract available in PubMed .

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Local Anesthetics: Differential Sensitivity of Nerve Fibers01:24

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Local anesthetics (LAs) block the sodium channels of nerve trunks, sensory nerve endings, and neuromuscular junctions. Although LAs can block all kinds of nerves, the sensitivity of nerve fibers differs according to nerve types and structures. LAs are known to block myelinated fibers faster than unmyelinated ones. Also, they block pain or sensory neurons at low concentrations without affecting the motor neurons involved in muscle contractions. This helps relieve labor pain without affecting the...
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