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Updated: Jul 31, 2026

Dissecting Host-virus Interaction in Lytic Replication of a Model Herpesvirus
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[一种新型mRNA疫苗在小鼠中的发育和免疫性评估,表达单纯疹病毒2型包膜糖蛋白gD]

Jialuo Bing1, Liye Jin1, Yao Deng2

  • 1School of Public Health, Xinxiang Medical University, Xinxiang 453003, Henan, China.

Sheng wu gong cheng xue bao = Chinese journal of biotechnology
|August 28, 2025
PubMed
概括

一种新型的脂多复合递送mRNA疫苗 (gD-ORI mRNA) 显示出预防生殖器疹的潜力. 这种针对人类阿尔法疹病毒2 (HSV-2) 的疫苗在小鼠中诱导了强烈而持久的抗体和T细胞反应.

关键词:
封面糖蛋白 gD简单性疹病毒2型免疫反应脂多复合体mRNA疫苗的使用情况

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Genital Herpes01:23

Genital Herpes

Genital herpes is a sexually transmitted infection primarily caused by herpes simplex virus type 2 (HSV-2), though herpes simplex virus type 1 (HSV-1) is increasingly implicated in genital infections, particularly among younger populations. Transmission occurs mainly through sexual contact, with asymptomatic viral shedding serving as a major route of spread. This characteristic makes HSV-2 difficult to control at a population level, as individuals may unknowingly transmit the virus even in the...