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Updated: Sep 9, 2025

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基于单核酸多态性的阿片类止痛药的个性化使用情况对照研究

Jing Yang1,2, Lei Zheng1, Fu Zheng2

  • 1Department of Pharmacy, Shandong Provincial Third Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.

Frontiers in pharmacology
|August 28, 2025
PubMed
概括

在服用阿片类止痛药的患者中,OPRM1的遗传变异与药物不良反应 (ADR) 的增加有关. 需要个性化药物治疗策略,特别是对于OPRM1AA基因型携带者,以提高安全性和有效性.

关键词:
药物不良反应药物剂量需求类阿片类止痛药个性化药物一个核酸多态

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