在口腔外科手术后的术后养状态和唾液细菌负荷之间的关系
Teruyuki Niimi1, Sakiko Soutome2, Akira Imakiire2
1Division of Research and Treatment for Oral and Maxillofacial Congenital Anomalies, School of Dentistry, Aichi Gakuin University, Nagoya, JPN.
Cureus
|August 28, 2025
概括
系统性抗生素有效地减少了口腔手术后的唾液细菌. 然而,减少口服可能会增加细菌数量,强调在饮食过渡期间需要加强口腔卫生,以预防手术部位感染 (SSI).
科学领域:
- 口腔和面外科
- 微生物学
- 传染性疾病
背景情况:
- 由于唾液细菌,口腔和部外科手术会造成易受手术部位感染的干净受污染的伤口.
- 术后养状态对唾液细菌负荷的影响尚不清楚.
研究的目的:
- 在接受口腔手术的患者中研究术后养状况和唾液细菌数量的关系.
- 评估系统性抗生素在不同饮食阶段对唾液细菌水平的影响.
主要方法:
- 在24名 (≥6年) 接受口腔手术并接受术后肠道养的患者中进行的前性观察研究.
- 使用16S rRNA基因实时PCR测量了手术前和液体,肠道和常规饮食阶段的唾液细菌数量.
- 用于统计分析的配对t测试.
主要成果:
- 在肠道养期间,全身抗生素维持了手术前的唾液细菌水平 (101%).
- 在服用抗生素时,细菌数量降低了88%,但在不服用抗生素时增加了122%.
- 在常规饮食阶段,数量恢复到基线 (98%).
结论:
- 系统性抗生素对于抑制口腔手术后的唾液细菌生长至关重要.
- 减少口服,特别是在饮食过渡期间,可能导致细菌负担增加.
- 建议实施额外的口腔卫生措施以减轻SSI风险.
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