蒙特卡洛模拟平台用于激光多普勒流量计
David Thompson1, Wietske Verveld1, Guillaume Lajoinie2
1University of Twente, TechMed Centre, Biomedical Photonic Imaging Group, Enschede, The Netherlands.
Journal of biomedical optics
|August 28, 2025
概括
一个新的无声波蒙特卡洛模拟器,MC-多普勒,准确地模拟了高分散生物样本中的透射激光多普勒流量计 (LDF) 的光传播.
科学领域:
- 生物医学光学
- 计算机建模
- 流体动力学
背景情况:
- 蒙特卡洛模拟对于模拟生物医学应用的杂介质中的光传播至关重要.
- 现有的基于voxel的平台面临着曲线边界和有限的流量和散射特性定制的问题.
- 通过传输激光多普勒流量测量 (LDF) 在高度分散的样本中未得到充分研究,尽管它对实验室芯片和线内流量传感具有相关性.
研究的目的:
- 开发一个新的无声波蒙特卡洛模拟平台,MC-多普勒,用于高分散介质的透射LDF.
- 通过比较模拟和实验多普勒功率光谱来验证模拟的准确性.
主要方法:
- 使用单元向量和光线跟踪进行光传播的MC-多普勒.
- 实现完全可定制的散射相函数和流量场.
- 用玻璃管中的聚乙烯珠悬浮体在不同流量 (0-15毫升/分钟) 中测试平台.
主要成果:
- 模拟和实验多普勒功率光谱显示散射系数高达5毫米-1.
- 在10mm-1的散射系数附近观察到差异.
结论:
- 通过MC-多普勒提供精确的光传播模拟.
- 该平台对中等散射系数有效,在具有挑战性的生物流体应用中推进流量量化.
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