具有抗菌性和快速静血性质的四元化素基纳米复合水凝
Juanni Zhang1, Farhan Mohd Said1, Ruixue Lv2
1Faculty of Chemical and Process Engineering Technology, Universiti Malaysia Pahang Al-Sultan Abdullah Lebuh Persiaran Tun Khalil Yaakob 26300 Kuantan Pahang Malaysia farhan@umpsa.edu.my.
RSC advances
|August 28, 2025
概括
这项研究介绍了一种基于酸盐的新型四元化纳米复合水凝,显示出增强的机械强度和强大的抗菌特性,适用于生物医学应用.
科学领域:
- 材料科学
- 生物医学工程
- 聚合物化学
背景情况:
- 水凝是一种多功能生物材料,可用于伤口治疗.
- 开发具有提高机械强度和抗菌性能的水凝对于先进的生物医学应用至关重要.
- 四元化酸盐和酸盐纳米胡须为凝增强提供独特的特性.
研究的目的:
- 使用双网络和纳米复合材料技术开发基于酸盐的四元化纳米复合材料水凝.
- 研究四元化酸盐 (QCS),酸盐纳米胡须 (ChWs) 和Zn2+对水凝特性的影响.
- 评估开发的水凝的机械强度,胀行为,抗菌活性,生物相容性和静血能力.
主要方法:
- 四元化酸盐 (QCS) 和酸盐纳米胡须 (ChWs) 的合成和表征.
- 在QCS,ChWs和Zn2+的存在下,通过烯酸 (AA) 和烯胺 (AM) 的基聚合构建水凝.
- 使用FT-IR和SEM进行化学结构和形态分析;对成分对物理和生物性能的系统研究.
主要成果:
- 这些水凝表现出了显著的三维网络结构.
- 增加的QCS含量显著提高了机械性能,25%的QCS产生了391.9kPa的拉伸强度和495%的断裂延伸.
- 增强的QCS和Zn2+含量导致抗菌率高 (高达99%对抗大肠杆菌和黄金杆菌),并显示出良好的生物相容性和血静性.
结论:
- 开发的基于酸盐的四元化纳米复合水凝具有出色的机械强度,抗菌活性和静血性能.
- 双网络和纳米复合材料技术的结合为制造先进的水凝提供了有前途的策略.
- 这些水凝具有重要的生物医学应用潜力,包括伤口治疗,静血材料和感染控制.
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