Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

2.9K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.9K
Diabetes: Symptoms, Diagnosis, and Complications01:15

Diabetes: Symptoms, Diagnosis, and Complications

685
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
685
Diabetes Mellitus: Overview and Type I Subtype01:22

Diabetes Mellitus: Overview and Type I Subtype

3.2K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
3.2K
Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

1.2K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
1.2K
Carbohydrate Metabolism01:36

Carbohydrate Metabolism

11.7K
Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
11.7K
Diabetes: Management and Pharmacotherapy01:15

Diabetes: Management and Pharmacotherapy

354
The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
354

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Impact of Technology Introduction on Glycemic Control of People Living with Type 1 Diabetes in Belgium: An Observational, Real-World Study.

Diabetes technology & therapeutics·2026
Same author

Development of a comprehensive real-world evidence dataset to inform diabetes policy: the diabetes data cell project.

BMC public health·2026
Same author

Simplified Switching to Once-Weekly Insulin Icodec Without an Initial One-Time Additional Dose Versus Once-Daily Insulin Glargine U100 in Basal Insulin-Treated Type 2 Diabetes (ONWARDS 10): A Randomised Controlled Trial.

Diabetes, obesity & metabolism·2026
Same author

Advancing Early-Stage Type 1 Diabetes Care: Future Focused Pathways for Identification, Screening, Diagnosis, and Monitoring.

Diabetes, obesity & metabolism·2026
Same author

GLP1-E2 therapy delays autoimmune diabetes in late-stage prediabetic NOD mice and potentiates low-dose anti-CD3 therapy for enhanced disease protection.

Diabetologia·2026
Same author

An international consensus on screening and monitoring early-stage type 1 diabetes: A roadmap to European implementation.

Diabetes, obesity & metabolism·2026

相关实验视频

Updated: Sep 9, 2025

Author Spotlight: Understanding Retinal Vessel Resilience and Disease Progression
04:36

Author Spotlight: Understanding Retinal Vessel Resilience and Disease Progression

Published on: January 12, 2024

1.2K

糖尿病发病时代在国家护理系统对1型糖尿病患者视网膜病变和小白膜尿病的患病率的影响:诊断后15年的一项横截面实践观察研究

Astrid Lavens1, Christophe De Block2, Philippe Oriot3

  • 1Health Services Research, Sciensano, Brussels, Belgium.

Diabetes, obesity & metabolism
|August 28, 2025
PubMed
概括
此摘要是机器生成的。

在诊断后15年,改善了1型糖尿病 (T1D) 的治疗,显著减少了视网膜病变和白膜尿等微血管并发症. 1998年以后被诊断出患有并发症的人较少,尤其是11岁以后出现并发症的人.

关键词:
微血管并发症现实世界数据一类糖尿病

更多相关视频

Studying Diabetes Through the Eyes of a Fish: Microdissection, Visualization, and Analysis of the Adult tgfli:EGFP Zebrafish Retinal Vasculature
10:07

Studying Diabetes Through the Eyes of a Fish: Microdissection, Visualization, and Analysis of the Adult tgfli:EGFP Zebrafish Retinal Vasculature

Published on: December 26, 2017

13.5K
Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats
07:41

Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats

Published on: October 23, 2020

6.0K

相关实验视频

Last Updated: Sep 9, 2025

Author Spotlight: Understanding Retinal Vessel Resilience and Disease Progression
04:36

Author Spotlight: Understanding Retinal Vessel Resilience and Disease Progression

Published on: January 12, 2024

1.2K
Studying Diabetes Through the Eyes of a Fish: Microdissection, Visualization, and Analysis of the Adult tgfli:EGFP Zebrafish Retinal Vasculature
10:07

Studying Diabetes Through the Eyes of a Fish: Microdissection, Visualization, and Analysis of the Adult tgfli:EGFP Zebrafish Retinal Vasculature

Published on: December 26, 2017

13.5K
Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats
07:41

Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats

Published on: October 23, 2020

6.0K

科学领域:

  • 内分泌学和糖尿病治疗
  • 公共卫生研究
  • 眼科和科

背景情况:

  • 1型糖尿病 (T1D) 管理已经发展,需要了解诊断时代如何影响长期的微血管并发症率.
  • 诊断后15年评估结果为当代T1D护理模式的有效性提供了关键的见解.

研究的目的:

  • 评估糖尿病发病时代对T1D患者糖尿病视网膜病变和白色素尿的患病率的影响.
  • 在一个结构化的医疗保健系统中,在不同时期诊断的队列之间比较微血管并发症率.

主要方法:

  • 分析了2176名30岁前被诊断为T1D的人的数据.
  • 两个群体的比较:A组 (1985-1998年开始) 和B组 (1998-2009年开始).
  • 使用概括估计方程评估糖尿病视网膜病变和白膜尿的患病率.

主要成果:

  • 在A组,血糖控制 (HbA1C) 和LDL胆固醇较差;在B组,肥胖率较高.
  • 糖尿病视网膜病变的患病率显著下降,从2001年的36. 3%降至2022年的21. 1% (p< 0. 0001).
  • 从2001年的14. 9%降低到2022年的7. 3% (p<0. 05),特别是在11岁以后发病的患者中.

结论:

  • 1998年以后被诊断为T1D的个体在诊断后15年出现的微血管并发症较少.
  • 在11岁以后出现T1D的患者中观察到视网膜病变的显著减少.
  • 这些发现强调了糖尿病治疗的进步对患者长期健康状况的积极影响.