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Updated: Sep 9, 2025

Electrophysiological Assessment of Murine Atria with High-Resolution Optical Mapping
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结构与细胞重塑在心房节律失调中的作用:个性化数字双胞胎的见解

Andrey V Pikunov1,2, Roman A Syunyaev3, Rheeda Ali4

  • 1Independent Researcher (A.V.P.).

Circulation. Arrhythmia and electrophysiology
|August 28, 2025
PubMed
概括

这项研究揭示了细胞水平的电变化如何导致纤维化心脏中的心房动 (AF). 一个新的算法准确地预测AF驱动器的形成, 帮助理解和治疗这种渐进的心律障碍.

关键词:
动作潜力心房动疾病的进展纤维化肺静脉 肺静脉

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Mechanism of Cardiac Arrhythmias

Arrhythmias are irregular heart rhythms occurring when the heart's electrical impulses become abnormal. These disturbances can lead to various symptoms, depending on their severity and the underlying cause. Some common factors contributing to arrhythmias include hypoxia, ischemia, electrolyte imbalances, excessive catecholamine exposure, drug toxicity, and muscle overstretching. Arrhythmias can be classified into two main types based on the rate and site of origin of abnormal heart rhythms.
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