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经过手术治疗的下肢软组织肉瘤患者的功能和瘤结果

Zeyneb İrem Yuksel Salduz¹, Yaşar Samet Gökçeoğlu², Ayşe Nur İncesu²

¹Department of Family Medicine, Faculty of Medicine, Bezmialem University, Istanbul, Turkiye.

Cancer control : journal of the Moffitt Cancer Center

|August 28, 2025

概括

与新辅助放射治疗相比,辅助放射治疗改善了下肢软组织肉瘤患者的功能结果和生活质量. 瘤的位置和转移会影响生理结果.

科学领域:

整形医学
外科瘤学
辐射瘤学

背景情况:

软组织瘤显著影响患者的结果和生活质量.
手术是下肢软组织瘤的基石.

研究的目的:

在手术治疗下肢软组织肉瘤患者中研究影响瘤和功能结果的因素.
为了比较新辅助和辅助放射治疗的结果.

主要方法:

对52名下肢软组织肉瘤患者的回顾性分析 (2016-2022年).
患者接受了新辅助或辅助放射治疗的外科切除.
使用QLQ-C30评估生活质量 (QoL);使用肌肉骨瘤协会 (MSTS) 和多伦多极端救生得分 (TESS) 评估功能结果.

主要成果:

与新辅助放射治疗相比,辅助放射治疗与显著更高的MSTS和TESS得分相关.
接受辅助放射治疗的患者报告QLQ- C30得分更好,包括身体,角色和社会功能.
在多变量分析中,5年总生存率为72%,局部控制为69%;转移是总生存率的唯一显著预测因素.

结论:

盆腔瘤的位置和转移与下肢软组织瘤的癌症结果较差有关.
使用常规分离的辅助放射治疗,与低分离的新辅助放射治疗相比,显示出更好的功能结果和QOL.

关键词:

下肢的部分生活质量辐射治疗癌症癌症软组织

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