患者脆弱性对喉切除术后的发病率,死亡率和整体存活率的影响
Eoin F Cleere1, Justin M Hintze1, David Brinkman1
1Department of Head and Neck Surgery, St James's Hospital, Dublin, Ireland.
概括
在喉切除手术后, 虚弱会显著增加并发症和更长的住院时间. 然而,在本研究中,虚弱并没有影响整体存活率.
科学领域:
- 癌症学
- 老年学
- 手术的结果
背景情况:
- 喉切除手术对患者的发病率和生存存在重大风险.
- 评估手术前的患者因素对于优化手术结果至关重要.
研究的目的:
- 评估虚弱对喉切除术后患者发病率和存活率的影响.
- 确定脆弱性评估是否可以识别具有较高不良结果风险的患者.
主要方法:
- 在10年内对233名接受喉腔切除术的患者进行了回顾性队列研究.
- 使用5项修改的脆弱性指数 (5mFI) 评估脆弱性.
- 使用多变量回归和案例匹配分析.
主要成果:
- 35. 2% 的患者被确定为虚弱,平均年龄更高.
- 虚弱的患者患上喉皮瘤的可能性增加,住院时间延长,非家庭出院.
- 在脆弱和非脆弱患者的3年整体存活期没有显著差异.
结论:
- 经过5项修改的脆弱性指数 (5mFI) 可以识别术前并发症风险增加的患者.
- 喉切除前的脆弱性评估可能会指导术后加强支持的需要.
- 针对脆弱患者的向干预可以优化手术结果.
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