一次访问后血压变化和心血管结果:系统性审查和剂量反应元分析
Mifetika Lukitasari1,2, Jitendra Jonnagaddala1,3,4, Siaw-Teng Liaw1,4
1School of Population Health, UNSW Sydney, NSW 2052 Australia.
European journal of preventive cardiology
|August 28, 2025
概括
使用电子健康记录 (EHR) 来可靠预测心血管疾病 (CVD) 风险. 较高的VVVBPV表明心血管疾病风险增加,支持其临床整合.
科学领域:
- 心脏病和心血管疾病
- 医疗信息学和电子健康记录
- 生物统计学和流行病学
背景情况:
- 访问到访问的血压变化 (VVV BPV) 是一个未充分利用的心血管疾病 (CVD) 风险因素.
- 电子健康记录 (EHR) 数据对于估计BPV和预测心血管疾病的可靠性是不确定的.
- 这项研究需要比较BPV估计方法及其CVD预测准确度.
研究的目的:
- 使用电子健康记录与非电子健康记录的BPV估计方法进行比较.
- 检查VVBPV和心血管疾病风险之间的剂量反应关系.
- 评估EHR数据对BPV评估的临床有用性.
主要方法:
- 在2012年1月至2024年8月期间发表的研究的系统审查和元分析.
- 包括评估成人VVBPV及其与心脏病结局的研究.
- 用于评估与心血管疾病风险相关的BPV值的剂量反应元分析 (DRMA).
主要成果:
- 在4926项查中,有49项研究符合纳入标准.
- 发现VVVBPV可预测心血管疾病的结局,EHR (HR: 1.17) 和非EHR (HR: 1.14) 数据之间的效果大小可比.
- 血压值SD≥6. 72mmHg或CV≥9. 05%与10%更高的心血管疾病风险相关.
结论:
- 电子病历数据可靠地估计了VVBPV,显示了与非电子病历来源相似的心血管疾病预测能力.
- 存在非线性剂量反应关系,高VVBPV显著增加心血管疾病风险.
- 应将VVBPV纳入临床实践,需要进一步研究实施策略.
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