相关实验视频

Updated: May 11, 2026

Multiplexed Immunofluorescence Analysis and Quantification of Intratumoral PD-1+ Tim-3+ CD8+ T Cells
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Multiplexed Immunofluorescence Analysis and Quantification of Intratumoral PD-1+ Tim-3+ CD8+ T Cells

Published on: February 8, 2018

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在具有瘤的小鼠中,IFNγ诱导的PD-L1+MHC II+巨细胞和Tim-3+瘤反应性CD8+T细胞预测了对抗PD-1治疗的反应

Jelena Gabrilo1, Sylvie Vande Velde2, Coralie Henin3

  • 1ULB Center for Research in Immunology, Gosselies, Belgium.

Cancer immunology research
|August 28, 2025
PubMed
概括

在瘤微环境 (TME) 中CD8+T细胞的高Tim-3表达和特异性骨髓细胞分化预测了抗PD-1免疫疗法的积极反应. 了解这些因素可以提高癌症治疗效率.

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相关概念视频

Tumor Immunotherapy01:27

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.