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Updated: Sep 9, 2025

Purification of Viral DNA for the Identification of Associated Viral and Cellular Proteins
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Purification of Viral DNA for the Identification of Associated Viral and Cellular Proteins

Published on: August 31, 2017

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在静止的HSV-1基因组中产生多个远程cis相互作用的CTCF绝缘体依赖的病毒染色体域

Alyssa Richman1, Sophie Kogut1, Terri Edwards2

  • 1Department of Biomedical and Health Sciences, University of Vermont, Burlington, Vermont, USA.

mBio
|August 28, 2025
PubMed
概括

在HSV-1基因组中的CCCTC结合因子 (CTCF) 隔离剂组织染色质循环,调节病毒基因表达. 删除CTRL2隔离器会改变这种结构,从而创造出更容易访问的病毒基因组并影响潜伏时间.

关键词:
4C-seq 其他美国在CTCF在HSV染色体表观遗传学绝缘体延迟时间病毒隔离剂

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