酸特异性酸 (Kgp) 的P. 通过禁用干扰素途径促进病毒感染

Ewelina Dobosz1, Anna Golda1,2, Michal Kanoza1,3

  • 1Department of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland.

mBio
|August 28, 2025
PubMed
概括

牙周炎 (PD) 通过破坏干扰素反应,增加病毒传播,加剧了简单疹病毒-1 (HSV-1) 感染. 一个关键的PD病原体 Porphyromonas gingivalis 使用Kgp gingipain来削弱抗病毒防御,促进HSV-1的传播和重新激活.

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