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Updated: Sep 9, 2025

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增长激素强烈诱导hSMN2促进体在哺乳动物细胞中的基因表达

Dilara Yücedal1, Ahmet Arman2

  • 1Department of Medical Genetics, Institute of Health Sciences, Marmara University School of Medicine, İstanbul, Türkiye.

Journal of clinical research in pediatric endocrinology
|August 28, 2025
PubMed
概括

增长激素 (GH) 可以影响人类SMN2 (hSMN2) 基因的表达,这是脊髓肌肉缩 (SMA) 治疗的关键因素. 这项研究表明GH调节hSMN2促进剂的活性,这表明它对SMA的潜在治疗用途.

关键词:
脊柱肌肉缩遗传性疾病增长激素生存运动神经元2促进体生存运动神经元蛋白

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Reporter Genes02:11

Reporter Genes

Reporter genes are a type of protein-coding gene that are often tagged to a gene of interest. Once inside a target cell, reporter genes usually produce visually identifiable characteristics like fluorescence and luminescence when expressed along with the gene of interest. Thus, reporter genes “report” the presence or absence of genes of interest in an organism, determine the gene expression pattern, or track the physical location of a DNA segment or protein in the cell.
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