评估药物差异和危害:在全州医疗保健系统中使用电子处方的协作药剂师配对队列研究
Hana Amer1,2, Sally Marotti3,4, Joshua M Inglis5,6
1Quality Use of Medicines and Pharmacy Research Centre, UniSA Clinical and Health Sciences, University of South Australia, GPO Box 2471, Adelaide, SA, 5001, Australia. hana.amer@mymail.unisa.edu.au.
International journal of clinical pharmacy
|August 28, 2025
概括
在医院使用电子处方系统的合作药剂师显著减少了药物错误和潜在的患者伤害. 这种模式提高了药物安全性和专业间的合作.
科学领域:
- 药理学和药房实践
- 医疗服务研究
- 患者安全
背景情况:
- 合作药剂师处方模式包括药剂师,医生和患者在药物管理中.
- 关于它们对电子处方系统 (EPS) 药物差异的影响的证据有限.
研究的目的:
- 评估合作药剂师处方对药物差异和潜在患者伤害的影响.
- 这项研究是在使用EPS的全州医疗保健系统中进行的.
主要方法:
- 一项对240名患者进行的多部位匹配队列研究 (120名合作处方,120名常规治疗).
- 患者根据人口统计,临床因素和入院前药物数量进行匹配.
- 通过使用HAMEC工具,检查电子病历以查找未经记录的药物差异;评估潜在危害.
主要成果:
- 合作药剂师处方导致每种药物 (RR 0.04) 和每位患者 (RR 0.23) 的未经证实的差异显著减少.
- 与常规治疗组中的8例相比,在协作处方组中没有严重或严重的伤害与差异相关.
结论:
- 在医院实施协作药剂师处方可以减少药物差异和潜在的患者伤害.
- 这种模式提供了一种改善药物安全和专业间合作的实用策略,支持全球向电子处方转变.
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