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Updated: Sep 9, 2025

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对CALM-AF10诱导的白血病的发展和维持至关重要

Yoko Kuroki1,2,3, Kazutsune Yamagata2,4, Yukiko Aikawa2

  • 1Center for Translational Research, Fujita Health University, Aichi, Japan.

Cancer science
|August 28, 2025
PubMed
概括

在CALM- AF10急性髓性白血病 (AML) 开始和进展方面,CCCTC结合因子 (CTCF) 是至关重要的. 抑制转胺酶2 (TGM2),这是CTCF的关键下游标,有效地阻止AML细胞的生长并促进分化.

关键词:
在CALM-AF10CCCTC的约束因素转胺酶 2急性骨髓性白血病表观遗传调节

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