世界卫生组织对淋巴结,脏和胸腺细胞病理的报告系统 - - 第一部分:淋巴结
Acta cytologica
|August 28, 2025
概括
淋巴结细针吸收活检 (FNAB) 是一个有价值的诊断工具. 世界卫生组织 (WHO) 报告系统标准化了淋巴结细胞病理学,提高了全球的诊断准确性和患者护理.
科学领域:
- 细胞病理学
- 癌症学
- 诊断病理学
背景情况:
- 淋巴结细针吸收活检 (FNAB) 是评估淋巴结病的常见方法,具有速度,低成本和最小侵入性等优势.
- FNAB样本支持各种辅助测试,包括微生物学研究,瘤的免疫细胞化学和疑似淋巴瘤的流细胞计.
- 在淋巴结病理学中越来越多地使用FNAB,因此需要一个标准化的报告系统.
研究的目的:
- 介绍和解释世界卫生组织 (WHO) 淋巴结,脏和胆囊细胞病理报告系统 (WHO系统).
- 要突出WHO系统如何根据细胞病理学发现标准化淋巴结病变分类.
- 通过更清晰,更一致的报告,强调该系统在减少诊断变异性和改善患者管理方面的作用.
主要方法:
- 世卫组织系统将淋巴结病变分为五个诊断类别:不充分/不充分/非诊断性,良性,非典型,可疑恶性和恶性.
- 细胞形态与临床成像数据的整合对于区分良性病变和恶性病变至关重要.
- 该系统推快速现场评估 (ROSE),以提高诊断准确性并减少重复程序.
主要成果:
- 世卫组织系统提供了标准化和可靠的方法来对淋巴结病变进行分类,从而使诊断更加准确和可重复.
- 通过减少诊断不确定性,该系统有助于更好的临床管理和治疗决策.
- 恶性瘤 (ROM) 的风险因诊断类别而异,在"可疑恶性瘤"和"恶性瘤"类别中风险较高.
结论:
- 世卫组织系统代表了淋巴结细胞病理学标准化的重大进展,改善了跨学科沟通和风险分层.
- 在管理不足的样本和解释异常病变方面仍然存在挑战,需要多学科的方法.
- 世卫组织系统是诊断各种淋巴结病理的重要工具,可在全球范围内应用,以优化治疗决策.
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