揭开疫苗进展的弧度
1Seth Berkley is an adviser to the Pandemic Center and Adjunct Professor at the School of Public Health, Brown University, Providence, RI, USA.
概括
从历史上看,高婴儿死亡率显著缩短了预期寿命. 最近的全球数据显示出一个鲜明的对比,儿童存活率的改善与疫苗接种率的增加有关.
科学领域:
- 历史人口统计
- 公共卫生
- 流行病学
背景情况:
- 由于婴儿死亡率高,1651年的预期寿命很低 (37-40岁),伦敦每1000个活产婴儿中有251个死亡.
- 传染病严重影响了早期的美国殖民地生存,特别是在南方.
- 五十年前,全球婴儿死亡率大约是每1000个活产婴儿就有100个,
研究的目的:
- 突出历史背景的低预期寿命和高婴儿死亡率.
- 强调传染病对儿童生存的影响.
- 通过疫苗接种等干预措施,
主要方法:
- 对预期寿命和婴儿死亡率的历史人口数据进行分析.
- 对殖民美洲传染病的流行病学记录进行审查.
- 对过去50年婴儿死亡率和接种疫苗的全球卫生统计数据进行检查.
主要成果:
- 历史数据证实17世纪英格兰和早期美国殖民地的婴儿死亡率极高.
- 传染病是这些时期死亡的主要原因.
- 全球婴儿死亡率显著下降,同时疫苗的可用性增加.
结论:
- 历史上的预期寿命因婴儿死亡率高而大幅缩短.
- 儿童生存率的提高与公共卫生和广泛的疫苗接种计划的进步密切相关.
- 全球卫生领域的持续努力对于进一步降低婴儿死亡率和提高全球儿童存活率至关重要.
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