相关实验视频

Updated: May 7, 2026

Protocol for Microplastics Sampling on the Sea Surface and Sample Analysis

Protocol for Microplastics Sampling on the Sea Surface and Sample Analysis

Published on: December 16, 2016

微塑料和人类生育能力:对它们在人类样本中的存在和生殖影响的全面审查

Bogdan Doroftei¹, Alexandra Savuca², Ana-Maria Cretu³

¹Origyn Fertility Center, Palace Street No. 3C, Iasi 700032, Romania; Department of Mother and Child Care, University of Medicine and Pharmacy "Grigore T. Popa", University Street No. 16, Iasi 700115, Romania; Clinical Hospital of Obstetrics and Gynecology "Cuza Voda", Cuza Voda Street No. 34, Iasi 700038, Romania; Department of Obstetrics and Gynecology, Faculty of Medicine, University of Medicine and Pharmacy "Grigore T. Popa", University Street, No. 16, Iasi 700115, Romania.

Ecotoxicology and environmental safety

|August 28, 2025

概括

微塑料 (MP) 和纳米塑料 (NP) 是人类样本中发现的环境污染物,可能会影响生殖健康. 本综述探讨了它们与不孕症的联系,并引用了关于毒性机制和人类暴露途径的动物研究.

科学领域:

环境科学
毒理学
生殖生物学

背景情况:

不孕症是全球日益严重的健康问题,
微塑料 (MP) 和纳米塑料 (NP) 是人类生物样本中检测到的普遍污染物,表明系统性暴露.
有证据表明,MP/NP可以跨越人类的生物障碍,并且可以跨代转移.

研究的目的:

对MP/NP暴露与人类不孕症相关的现有文献进行批判性审查.
检查MP/NP的动物模型研究,分子影响和人类暴露途径.
提供关于小型聚合物材料产生的生殖风险的综合观点.

主要方法:

对微塑料和纳米塑料暴露和生殖健康的科学研究进行文献审查.
分析研究毒性机制的动物模型的数据.
对人类生物样本和暴露途径的检查.

主要成果:

动物研究表明MP/NP有毒性,包括性腺变化,氧化应激,细胞亡和荷尔蒙功能障碍,通常取决于颗粒大小和聚合物类型.
在人体血液,胎盘和精液中检测到MP/NP.
目前的证据表明,MP/NP可能会影响人类的生殖功能.

结论:

通过各种有毒机制,暴露于微塑料和纳米塑料可能导致人类不孕.
在人类样本中检测MP/NP的标准化方法对于进一步的研究至关重要.
了解MP/NP毒性对于制定生殖健康问题的预防和治疗策略至关重要.

关键词:

不孕症微塑料纳米塑料生殖毒理学

更多相关视频

Ecotoxicological Effects of Microplastics on Bird Embryo Development by Hatching without Eggshell

Ecotoxicological Effects of Microplastics on Bird Embryo Development by Hatching without Eggshell

Published on: August 14, 2021

Sampling, Identification and Characterization of Microplastics Release from Polypropylene Baby Feeding Bottle during Daily Use

Sampling, Identification and Characterization of Microplastics Release from Polypropylene Baby Feeding Bottle during Daily Use

Published on: July 24, 2021

相关概念视频

Fertilization

Fertilization

During fertilization, an egg and sperm cell fuse to create a new diploid structure. In humans, the process occurs once the egg has been released from the ovary, and travels into the fallopian tubes. The process requires several key steps: 1) sperm present in the genital tract must locate the egg; 2) once there, sperm need to release enzymes to help them burrow through the protective zona pellucida of the egg; and 3) the membranes of a single sperm cell and egg must fuse, with the sperm...

Introduction to the Human Microbiota

Introduction to the Human Microbiota

Microorganisms colonize various regions of the human body, including the mouth, nasal passages, throat, stomach, intestines, urogenital tract, and skin. The total number of microbial cells is estimated to range from 10¹³ to 10¹⁴—comparable to, or exceeding, the number of human somatic cells. This host–microbiome relationship has led to the conceptualization of humans as supraorganisms, wherein microbial communities perform vital roles in development, immunity,...

Development of Human Microbiota

Development of Human Microbiota

The human microbiota begins developing at birth and undergoes continual change as we age. Infancy marks a critical period of microbial sensitivity, offering a “window of opportunity” during which beneficial microbes help mature the immune system. By age three, children typically develop a more stable and diverse microbial community. Newborns acquire microbes from their immediate environment; vaginal delivery favors maternal vaginal microbes, while cesarean births favor microbes from...